San Diego Business Journal

Shares of Orexigen Therapeutics Inc. leapt 50 percent after the San Diego company filed a patent for its recently approved weight loss drug Contrave, claiming it reduced heart disease.

Shares of Orexigen (Nasdaq: OREX) were trading at $5.78 per share at close on Monday. By 9:30 a.m. Wednesday, shares were trading at $8.69.