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Nasdaq , ARNA

Arena Pharmaceuticals, Inc. is a bio-pharmaceutical company with a pipeline of internally discovered, small-molecule product candidates that target G protein-coupled receptors. Arena Pharmaceuticals’ product candidates act on or through known and orphan GPCRs, and have been discovered using Arena Pharmaceuticals’ own GPCR-focused drug discovery technologies and capabilities. Two of the company’s product candidates are in clinical trials. APD356, being developed for the treatment of obesity, is in a phase II clinical trial. APD125, being developed for the treatment of insomnia, is in a phase I clinical trial. Arena Pharmaceuticals also has active collaborations with two pharmaceutical companies for the development of compounds targeted for the treatment of type 2 diabetes, and atherosclerosis and related disorders. These collaborative partners are Ortho-McNeil Pharmaceutical, Inc. and Merck & Co., Inc.


Total number of shares outstanding as of Sept. 9 35,300,000

Price of each share of common stock on Sept. 9 $9.20

Aggregate market value as of Sept. 9 $324,760,000

Performance Record

For year ended Dec. 31.

2004 2003 2002

Total revenues $13,685,822 $12,834,279 $19,421,765

Net income (loss) ($57,991,770) ($47,059,439) ($32,829,938)

Net income (loss) per share ($2.40) ($1.74) ($1.19)

Total assets $206,364,995 $229,898,109 $254,890,047


Jack Lief, 59, director since 1997.

Dominic Behan, 41, director since 2000.

Donald Belcher, 66, director since 2003.

Scott Bice, 62, director since 2003.

Harry Hixson Jr., 66, director since 2004.

J. Clayburn La Force Jr., 76, director since 2002.

Louis J. Lavigne Jr., 56, director since 2005.

Tina Nova, 51, director since 2004.

Executive Compensation

Officer 2004 Cash Compensation

Jack Lief, president and chief executive officer $653,750

Dominic Behan, senior vice president and chief scientific officer $370,000

Steven Spector, senior vice president, general counsel and secretary $335,000

William Shanahan Jr., vice president and chief medical officer $269,125

Louis Scotti, vice president, marketing and business development $241,000

Significant Stock Ownership

Number of shares Percent

March 31

Perry Capital LLC 2,806,154 8

Mainfield Enterprises, Inc. 2,805,765 8

Smithfield Fiduciary LLC 2,104,324 6

Dimensional Fund Advisors Inc. 2,019,932 5.7

TCW Business Unit 1,959,129 5.6

Directors and officers as a group (15 people) 2,750,085 7.4

Other Information

Headquarters: 6166 Nancy Ridge Drive, San Diego, CA 92121; (858) 453-7200; fax (858) 453-7210.

Web site: www.arenapharm.com.

Auditors: Ernst & Young LLP.

Employees: 291.

Industry: Drug manufacturers.

Information was compiled from the company’s annual and proxy reports.


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