Twenty one San Diego area businesses attracted about $220 million in venture capital during the third quarter, according to the Dow Jones VentureSource report.

The region ranked sixth highest in total venture capital dollars behind San Francisco, Boston, New York, Washington, D.C., and Los Angeles, which obtained about $890 million during the third quarter.

Nationally, there were 899 venture capital deals during the past quarter that came to about $11 billion in fundings. The dollar amount was down 24 percent from the prior quarter, but an increase of 16 percent from the like quarter of 2013, the report said.

San Diego-based Otonomy Inc., a biotechnology business developing drugs to treat ear disorders, was listed as the nation’s third largest initial public stock offering for the past quarter. The company raised about $100 million in an IPO that closed in August.