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Ligand to Buy Metabasis

Ligand Pharmaceuticals said Oct. 27 it has agreed to buy struggling San Diego biotech Metabasis for $3.2 million cash. After factoring in liabilities, Metabasis will receive approximately $1.8 million.

The La Jolla biotech, which warned earlier this year it may have to cease its operations entirely, was running out of cash and down to just a handful of employees.

The deal gives Ligand, developer of the painkiller Avinza and Promacta for low platelet levels, access to Metabasis’ HepDirect platform technology for drug delivery to the liver along with clinical stage drug candidates for diabetes, hyperlipidemia and liver diseases. An early-stage hepatitis C program is fully funded by Merck.

“Metabasis has built a pipeline of product candidates and drug development programs that have the potential to one day yield new therapies for metabolic and chronic liver diseases, but due to our limited financial and operational resources, we are unable to independently realize their full potential value,” said Metabasis CEO Mark Erion, who announced in September he was leaving the company for a job with Merck’s diabetes division.

The transaction, subject to regulatory and Metabasis shareholder approvals, is expected to close early next year.

In August, Ligand bought Branford, Conn.-based Neurogen for $11 million in stock and royalties that added psychiatric and neurological drugs to its portfolio.

— Heather Chambers

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  February 8-14, 2010
SDBJ News
CONNECT Goes to Washington
Most high-tech entrepreneurs and innovators don’t have time to put on a tie and sit through a three-hour meeting about policy issues in Washington, D.C. They are too busy creating the next generation of digital mobile applications and lifesaving health care products, and creating jobs for the new innovation economy. There has not been a strong voice or presence in the nation’s capital to represent these innovators, who neither have the money nor bandwidth to lobby or educate representatives on their needs and interests — until now.
S.D. Companies Race to Build Gene Machines
Technology contenders in the race to decode a person’s entire genetic makeup for less than $1,000 have been making gains in recent months, signaling that the finish line isn’t far ahead.
Conference Focuses on Methods to Combat Cyber Attacks
The creative and destructive power of the Internet emerged as a major topic of the West 2010 military conference, sharing the stage with more time-honored topics such as ships and naval strategy.
Scripps Health Issues $220M in Revenue Bonds
Scripps Health, currently in the middle of a building spree intended to bring its aging health care facilities up to date while accommodating future population demands, sought help financing its projects through the public markets last week.
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